Q: Who exactly must take aspirin? A: Patients with a history of new or recurrent atherosclerosis (e.g., heart attack, brain attack, or peripheral arterial disease) are at significantly increased risk for cardiovascular events and can cause related disease and even death, and these patients should take aspirin for secondary prevention (i.e., to prevent disease progression and events). Of course, effective secondary prevention measures for these diseases also include lifestyle modifications such as smoking cessation, weight control, increased physical activity, diet modification, and the application of pharmacological therapies to control blood pressure and cholesterol levels. Q: So, what kind of people are not suitable for taking aspirin? Do healthy people need to take aspirin as a health supplement to prevent blood clots? A: Aspirin should be contraindicated in the following patients: (1) ulcer disease with bleeding symptoms or other active bleeding; (2) people with hemophilia or thrombocytopenia or other bleeding tendencies; (2) ulcer disease or corrosive gastritis; (4) people with glucose 6 phosphate dehydrogenase deficiency, which is occasionally seen to cause hemolytic anemia; (5) patients with gout, aspirin can affect the action of other uric acid-removing drugs, and in small doses (5) Patients with gout, aspirin may affect the effect of other uric acid excretory drugs, and may cause retention of uric acid in small doses. (6) Healthy people do not need to take aspirin as a health drug, it may not necessarily prevent blood clots, but may increase the risk of bleeding.