Non-atrophic gastritis with sinus erosion is not severe, and most patients are often asymptomatic. Those with symptoms mainly present with non-specific dyspepsia symptoms such as epigastric pain or discomfort, epigastric distention, early satiety, belching and nausea. Patients with functional dyspepsia may or may not be associated with chronic gastritis. The histology of chronic gastritis can be significantly improved after eradication of H. pylori. The treatment of chronic non-atrophic gastritis with erosion is focused on relieving dyspeptic symptoms and improving inflammation of the gastric mucosa. For H. pylori-positive individuals, eradication of H. pylori is recommended both nationally and internationally. Therefore, H. pylori-positive chronic non-atrophic gastritis with sinus erosion with dyspeptic symptoms can be treated with H. pylori eradication. Since there is no clear relationship between clinical symptoms and those with chronic non-atrophic gastritis with sinus erosion. Therefore, treatment of symptoms is, in fact, empirical treatment of functional dysplasia. Chronic gastritis with bile reflux can be treated with prokinetic agents such as domperidone or gastric mucosal protectors with bile acid binding effects, such as magnesium aluminum carbonate preparations. Those with symptoms such as gastric mucosal erosion and acid reflux and epigastric pain can use acid-suppressing agents, H2 receptor antagonists or proton pump agents according to the severity of the disease or symptoms. Prokinetic drugs such as domperidone, mosapride and etopride hydrochloride can be used for those with epigastric fullness, nausea or vomiting as the main symptoms. Gastric mucosal protective agents, such as aluminum thioglycollate, rebapital, teprenone, and magnesium aluminum carbonate, are indicated for those with bile reflux, gastric mucosal damage, and those with significant symptoms. Antidepressants or anti-anxiety drugs can be used for chronic gastritis with significant psychiatric symptoms, accompanied by gastric sinus erosion. Treatment with herbal medicines can broaden the treatment pathway for chronic non-atrophic gastritis with gastric sinus erosion. In addition to symptomatic treatment, the above mentioned drugs are also useful for the repair of gastric mucosal epithelium and inflammation. The specific medication should be used in conjunction with clinical practice and under the guidance of a physician in an interview.