Duodenitis refers to inflammation occurring in the duodenum, and the main points of management are as follows: 1, pay attention to dietary regulation, patients need to avoid eating spicy, stimulating and cold diet, quit smoking, quit drinking, and keep three regular meals; 2, can consider doing carbon 13 or carbon 14 breath test to clarify the presence of H. pylori infection. If there is H. pylori infection, eradication treatment is recommended; 3, you can assist acid suppressing drugs, choose proton pump inhibitors or H2 receptor antagonists, such as omeprazole, rabeprazole, famotidine, ranitidine, etc. Supplemented with drugs to protect the gastric mucosa, such as magnesium aluminum carbonate, glutamine granules, etc., can promote the recovery of duodenal bullae; 4, patients also need to pay attention to rest and avoid strain. If duodenal bulla cannot be well treated and recovered, the condition may worsen and develop into duodenal ulcer, so patients need to pay attention to duodenal bulla conditioning treatment.