1.Surgical treatment: It is suitable for pituitary macroadenoma, microadenoma and non-invasive prolactin adenoma with clear boundaries. The advantage of surgery is to strive for total excision of the tumor and avoid long-term medication. In addition, surgery should be preferred for prolactin adenoma with cystic variant, which is not effective in drug treatment; surgery should be preferred for prolactin adenoma with pituitary stroke in magnetic resonance, which is not effective in drug treatment; surgery should be preferred for male patients, which is not effective in drug treatment; surgery should be preferred for mixed pituitary adenoma with mainly prolactin performance, but high GH and ACTH in laboratory test, which is not effective in drug treatment.
2.Drug therapy: bromocriptine or carte blanche, drugs have two main purposes to restore PRL to normal level, drugs can also reduce the size of tumor cells, but there is no clear evidence to confirm that drugs can kill tumor cells, so drug therapy often requires 3-5 years of treatment, and 2/3 of patients may relapse after stopping drugs. Drug therapy is suitable for those aggressive prolactin adenoma, or as a complementary treatment after surgical treatment.
3.Gamma knife treatment: as the last choice of treatment for prolactin adenoma.
4.Thyrotropinoma-TSH adenoma: It is rarely seen clinically and manifests as elevated TSH, elevated T3,T4, and the patient shows hyperthyroidism, which mainly needs to be differentiated from hypothyroidism-induced increased TSH and pituitary reactive hyperplasia.