Patients with atrophic gastritis with mild intestinalization can be treated symptomatically through medication and prophylaxis. Inflammatory diseases of the gastric mucosa are a common cause of the manifestations of this condition. Therefore, the type of pathogenic bacteria can be diagnosed by means of bacterial culture analysis, and then targeted antimicrobial agents can be used for anti-infective treatment, such as artificial oxymethonium metronidazole capsules, clarithromycin capsules, levofloxacin hydrochloride, etc. In addition, according to the patient’s actual symptoms, proton pump inhibitors, gastric mucosal protective agents, anticholinergic agents and other types of drugs for combined drug treatment, so as to relieve the patient’s gastric distension, acid reflux, nausea, chest pain, chest tightness and other adverse symptoms, the specific types of drugs are esomeprazole magnesium enteric tablets, gastric membrane capsule, atropine sulfate tablets, etc.. Patients need to maintain good living and eating habits during the treatment period, which have a positive impact on accelerating the recovery of the disease, such as a light diet, adequate regular rest, optimism, etc.