How is jaundice differentially diagnosed?

  The differential diagnosis of jaundice can theoretically be divided into three types: hepatocellular, obstructive, and hemolytic. However, in clinical work, due to the large individual differences, accompanied by many symptoms, especially in patients who have suffered from gallbladder stones, cholecystitis, sudden onset of jaundice, when it is very difficult to distinguish between the two. Acute biliary hepatitis, because of the clinical rarity, heavy jaundice, and delayed remission, but also often have some symptoms of extrahepatic obstruction, so it is difficult to think of this disease, it is easy to misdiagnose as extrahepatic obstructive jaundice for surgical treatment. On the basis of poor liver function and impaired bile excretion, surgery is blindly and hastily performed, which is bound to aggravate the damage to the liver and eventually lead to the patient’s death from failure. This lesson is often seen in clinical practice.  Jaundiced hepatitis is a special clinical type of viral hepatitis with intrahepatic bile as the main manifestation, which used to be called capillary bile duct hepatitis or small bile duct hepatitis, and can occur in patients with acute, chronic and severe hepatitis and post-hepatitis cirrhosis. The main clinical characteristics are deep jaundice, long duration, may be accompanied by generalized skin pruritus, stool color light or gray, and relatively light gastrointestinal symptoms and weakness. It can be clinically divided into acute biliary hepatitis and chronic biliary hepatitis.  Acute biliary hepatitis is a special type of acute viral hepatitis. In addition to the common manifestations of viral hepatitis, jaundice usually appears at the end of the first week of illness and peaks in the second and third weeks, accompanied by itching of the skin and lighter and greyer stools. It differs from general viral hepatitis: (a) jaundice is heavy and lasts for a long time (2-6 months), with “three separate” manifestations, i.e. jaundice is heavy, while gastrointestinal symptoms are light; jaundice peaks in 3-6 weeks, but transaminases decrease rapidly; jaundice is heavy, but the decrease in prothrombin activity is not obvious. (B) with extrahepatic obstructive features: the appearance of similar obstructive jaundice, but various special tests do not have evidence of extrahepatic obstruction. Acute biliary hepatitis and extrahepatic obstructive jaundice are treated very differently, so it is important to differentiate jaundice, especially in middle-aged and elderly patients with biliary hepatitis who are often misdiagnosed with extrahepatic obstructive jaundice. At this point, if a caesarean section is performed, it will add to the problem and lead to a worsening of the condition.