Parkinson’s disease, also known as tremor palsy, is one of the most common degenerative diseases of the central nervous system in middle-aged and elderly people. Scientific research on the etiology of Parkinson’s disease tends to relate to a combination of ageing, exposure to environmental toxins and genetic susceptibility. “Exposure to chemicals and long-term exposure to pesticides can cause Parkinson’s disease, and about a significant proportion of clinical Parkinson’s patients are caused by environmental ‘poisoning’.” The difference: hand shaking is not necessarily “Parkinson’s” “Some people obviously do not have Parkinson’s disease, but according to some medical books and medical knowledge, their hand and foot shaking symptoms forced to Parkinson’s disease.” Guo Li introduced that in the outpatient clinic, he often encountered some patients like this. But after the doctor’s examination, the patient’s hand and foot tremors were found to be due to other neurological diseases, not Parkinson’s disease. Parkinson’s disease is a degenerative disease of the nervous system, mainly manifested by slow movements, non-stop tremors in the hands and feet or other parts of the body, and the body becomes stiff. “In addition to tremor, there are other symptoms such as muscle stiffness and writing smaller and smaller.” According to the report, tremor is one of the most common and earliest symptoms of Parkinson’s disease. Tremor is generally referred to as resting tremor if it occurs when a person is at rest. “Most people with Parkinson’s disease have resting tremor, but patients who have tremors such as tremors of the hands, head and lower extremities are not necessarily Parkinson’s disease patients, and may also have idiopathic tremor and other genetic conditions. Also, it is normal for everyone to have tremors in their hands and feet when carrying heavy things or doing physical work, and this is not Parkinson’s disease”. If the idiopathic tremor occurs when the person is not resting and relaxing, it is scientifically called postural or motor tremor. In addition, such as hyperthyroidism, small tremors in the hands, which are faster and also accompanied by a fast heart rate, fatigue and weakness, and easy hunger to eat can also occur tremors. “Transient limb tremors may occur in cases of stress, anxiety and hypoglycemia, as well as in cases of excessive fatigue. If the limb or head tremor is prolonged, you can visit a specialist and ask your doctor to determine if it is Parkinson’s disease.” The cause of primary Parkinson’s disease is still not completely clear, it is generally believed that it is mainly related to ageing, genetics and environmental factors, especially the development of modern industry, some agricultural and industrial pollution may cause the disease, such as spraying pesticides on vegetables, hair dyes mixed with various chemical ingredients, etc., are causative factors. In this regard, he reminded that in daily life to pay special attention to avoid contact with some environmental risk factors. Reminder: slow walking and instability to seek early medical attention “Early identification of Parkinson’s disease is sometimes difficult. In clinical practice, many Parkinson’s patients have been underdiagnosed and misdiagnosed.” Some patients with Parkinson’s disease have non-motor symptoms in front of them, and it is impossible to confirm the diagnosis by non-motor impairment alone. In addition, because Parkinson’s disease is a disease of the elderly, many patients think they are “old and have trouble with their legs” when they develop motor disorders, and think they are “confused” when they have non-motor symptoms such as forgetfulness, anxiety and depression, missing the opportunity for early treatment. This is a missed opportunity for early treatment. Many patients initially think they have cervical spondylosis, lumbar spondylosis, depression, amnesia, etc., only to find out that they have Parkinson’s disease after further examination. When elderly people feel that they have a tendency to lean forward when walking, as well as unstable and slow footsteps, they should seek prompt medical attention. At the same time, because Parkinson’s disease requires a high level of medication from doctors in terms of treatment, the same patient should take different methods of medication dispensing at different stages, plus there are more drugs for Parkinson’s disease, many non-specialist doctors have some limitations in understanding the disease. Therefore, experts suggest that it is best for patients to visit the neurology department of a regular public hospital to obtain regular treatment. Parkinson’s disease is a chronic disease, although it can not be cured it, but can be long-term control of its symptoms, through comprehensive treatment can have a better quality of life in the long term. “Some patients can also develop the disease very quickly, so it is important to treat it early and require regular long-term medication, and to work with your primary care physician to develop an overall treatment plan that is right for you. During your visit, gradually become familiar with the various clinical manifestations of Parkinson’s disease and the main drugs currently used for treatment, and be prepared for a long-term battle with the disease.”