Palliative Care is a subdiscipline of medicine related to end-of-life care initiated by Christian people in 1960. It focuses on improving the quality of life of patients and helping their families to cope with the difficulties and problems of this time together. Hospice is closely related to palliative care, which refers to the medical, nursing, psychological, nutritional, religious, and social support provided to patients who are not expected to live more than six months, so that they can pass away as comfortably, dignified, prepared, and peaceful as possible in the last days of their lives. Palliative care has been translated as palliative care in China, which is not to give up treatment but to face the disease with the patient and family in a different way. The treatment principles of palliative care are: 1) to preserve life and recognize near death as a normal process; 2) not to accelerate or delay death; 3) to relieve pain and other distressing symptoms; 4) to provide physical, psychological, social and spiritual (i.e., physical, mental, social and spiritual) support to patients until their death; 5) to provide grief and other assistance to family members during the patient’s serious illness and death. Timing of palliative care interventions: Palliative care also does not have to wait until the last stage of life, but can be involved early in the disease and can be used in conjunction with other treatments to achieve the best results for the patient. For example, in advanced cancer patients with multiple metastases, the metastases cause local obstruction. At this time, there is little hope for chemotherapy to attempt to cure the disease, but minimally invasive methods such as puncture and laparoscopy can still be performed to resolve the obstruction, and palliative chemotherapy and palliative radiotherapy can be administered to relieve the obstruction and achieve improvement of the patient’s symptoms. For example, the use of diuretics to reduce edema, the administration of oxygen, the use of drugs to reduce respiratory secretions to improve the patient’s dyspnea, the use of morphine to relieve pain, etc., are all treatments of palliative care. Therefore, palliative care does not mean giving up treatment or stopping treatment, but focusing on improving the patient’s symptoms and relieving pain. Birth, old age, sickness and death are natural processes of life, but people often pay much attention to birth, but deliberately neglect old age, sickness and especially death. If oncology patients, especially to the last stage of life, how will it be a process and what should be done to prepare for this process smoothly and peacefully. In fact, this is a common problem that every person and family will face. Why can’t we change our mindset, plan our last moment in advance, tell your relatives and doctors, choose palliative care when facing incurable diseases, and live happily and die decently?