Novel coronavirus infection and cold cannot be completely distinguished by symptoms. In novel coronavirus infections, patients generally have fever, fatigue, dry cough and other symptoms of upper respiratory tract infection, and severe patients may have difficulty in breathing, but some patients may have mild symptoms without fever. The above symptoms are difficult to distinguish from the common cold, and are currently distinguished mainly by epidemiological history and pathogenetic testing. If you have a history of travel to the infected area or contact with people in the infected area within 14 days before the onset of the disease, you should go to the hospital to confirm the diagnosis if you have symptoms of upper respiratory tract infection. Early onset of the disease with normal or reduced total peripheral blood leukocyte count and detection of novel coronavirus nucleic acid in specimens such as pharyngeal swabs, lower respiratory secretions and blood can confirm the diagnosis of novel coronavirus infection.