Recently, the Department of Quadruple Surgery (Cardiothoracic and Vascular Surgery) of our hospital performed coronary artery bypass grafting for a senior patient with severe coronary artery disease and has been discharged from the hospital. The patient, Tan Moumei, female, 78 years old, was diagnosed as “1, coronary heart disease: unstable angina; 2, hypertension; 3, type 2 diabetes, diabetic nephropathy” on April 28, 2014 due to “recurrent chest tightness and shortness of breath for 2 years, aggravated for more than 10 days”. The coronary angiogram indicated “coronary artery left trunk and three vessels lesion”, considering that the coronary artery lesion is serious and not suitable for PCI, so we asked the deputy director of the Department of Surgery Xie Cuixian to consult, considering the indication of coronary artery bypass surgery, and transferred to the Department of Surgery IV. After sufficient conditioning and preoperative preparation, and the formulation of a thorough surgical plan and postoperative precautions, the patient underwent coronary artery bypass grafting under general anesthesia extracorporeal circulation on May 21, and the coronary blood flow improved immediately. According to the patient, she has four children, three of whom have emigrated abroad (one in the United States and two in Argentina), she lives in Guangzhou with her eldest son, and this hospitalization was taken care of by her eldest son and his daughter who came back from Argentina. They were very satisfied with the result and thanked the director and the medical staff for their careful treatment and care. According to Director Xie Cuixian, coronary artery bypass grafting can not only solve the problems faced by drug therapy and coronary stenting in the treatment of coronary artery disease, such as lesions at the branches of coronary arteries, multiple lesions in multiple branches, and lesions in the left main trunk, but is also the most complete and thorough way to reconstruct blood flow at present. The indications for the procedure include: 1) stenosis of the left main stem of the coronary artery, 2) significant stenosis of more than two coronary arteries, 3) recurrent stenosis after coronary artery shaping or stenting, 4) ventricular wall tumor formation or septal perforation after myocardial infarction, 5) patients requiring other cardiac surgery at the same time.