Li Guilin, Department of Neurosurgery, Xuanwu Hospital, Capital Medical University The tumor in the pineal region is deeply located and adjacent to important neurovascular, which makes surgery extremely risky. Usually patients choose radiation therapy. We use transversal longitudinal fissure, corpus callosum and intervallosal approach can remove the tumor completely. Especially in this case, the patient was a mature teratoma, which was not suitable for radiation therapy.