Chronic diseases that cannot be vaccinated with the new crown vaccine include neurological diseases, autoimmune diseases, acute exacerbations of chronic diseases and uncontrolled malignant tumors. 1. Neurological diseases: Guillain-Barre syndrome, uncontrolled epilepsy, convulsions, transverse myelitis, etc., cannot be vaccinated with the New Crown vaccine, and the vaccination may lead to morbidity of the patient or may aggravate the disease. 2. Autoimmune diseases: such as systemic lupus erythematosus, rheumatoid arthritis, anaphylactic purpura, etc. are not effectively controlled, and vaccination may cause disease recurrence. 3. Acute exacerbation of chronic diseases: such as asthma attack, severe hypertension, blood sugar fluctuation, lung infection, cardiac insufficiency, etc., need to wait until the condition is stabilized before vaccination. 4. Malignant tumors: those whose malignant tumors are not effectively controlled cannot be vaccinated with the new crown vaccine. Before vaccination, ask the medical staff for relevant information, do not hide it and tell them the truth. After vaccination, stay for observation for 30 minutes, and inform the physician or vaccination personnel of any abnormality.