Centripetal obesity is a type of obesity in which the distribution of body fat is centered on the trunk. The main manifestations are full-moon face, buffalo back (i.e. the back of the shoulder protrudes, back muscles obviously protrude), abdominal fat accumulation, fat pad in the supraclavicular fossa, and relatively thin limbs. Centripetal obesity is the result of increased glucocorticoid secretion. Glucocorticoid is a hormone secreted by the adrenal glands and regulated by the hypothalamic-pituitary-adrenal axis. Centripetal obesity is mainly seen in the following points: First, pituitary tumor patients, pituitary tumor can secrete ACTH, ACTH stimulates the adrenal glands, so that glucocorticoids increase to form centripetal obesity. Second, adrenal adenoma, adenocarcinoma, adrenal hyperplasia, etc. can cause the adrenal glands to secrete too much glucocorticoid hormone, forming centripetal obesity. Third, some patients because of rheumatoid arthritis, lupus erythematosus and other diseases, long-term use of glucocorticoids, can also appear medical source centripetal obesity.