From April 2002 to December 2004, we used cortriptyline in obstetrics and gynecology for continuous epidural gap block. From April 2002 to December 2004, we used cortisol for continuous epidural gap block in obstetrical delivery and obtained satisfactory results, which are reported as follows. Drug source: Jincheng Hess Pharmaceutical Co., Ltd, 500mg bottle of powder injection, product batch number 20020801. Preparation of drug solution: 500mg of cortisol was added to 25ml of 0.9% saline and diluted into 2.0% chloroprocaine hydrochloride solution, with 2 drops of epinephrine hydrochloride (approximate 1:200,000 million units). Case selection: A total of one woman aged ~ years, 163/167 cm, 61/58 kg, with no contraindication for epidural space block, who had to undergo cesarean section due to obstetric factors, was selected for L2~3 gap, and the epidural space was confirmed by resistance disappearance/bubble rebound method. The epidural catheter was placed 3 cm laterally to the head. anesthesia operation: preoperative intramuscular injection of atropine 0.01 mg/kg and valium 0.2 mg/kg. after admission, noninvasive blood pressure, electrocardiogram and pulse oximetry monitoring were connected, the lower limb vein of one side was opened with an 18-gauge trocar needle, and 300-400 ml of compound sodium lactate Ringer’s solution was infused. after left lateral recumbency and routine disinfection of the skin, the epidural was performed under giant anesthesia at T9-10 The epidural space was punctured by the same operator in the interval, and it was confirmed that the tip of the needle did reach the epidural space by the resistance disappearance and bubble rebound test, and there was no blood and cerebrospinal fluid in the retraction, and the catheter was placed into the head end for 3 cm, and then the catheter was properly fixed and injected with 4 ml of the aforementioned prepared drug solution via the catheter. 2 min after the test volume was injected, the skin was pricked with a 7# needle every 15 s to detect the hyperalgesia/disappearance (onset of effect time) After confirming the absence of lumbar anesthesia sign, the first dose of 13ml was injected at one time, and the first additional drug time (the first amount of action time) and the blocking range were determined by the increase of rectus abdominis muscle tension during the operation. Blood pressure, heart rate and pulse oxygen saturation values were recorded at the time of hyperalgesia/disappearance, after the block was perfected, skin incision, laparotomy, and the start of abdominal closure.