Pancreatitis necrosis belongs to severe pancreatitis, and severe pancreatitis is reversible, which is because severe pancreatitis has the possibility of cure, but it is more difficult to treat. Pancreatitis necrosis is often accompanied by hemorrhage, secondary infection shock and multiple organ failure complications, the condition is very dangerous, the prognosis is very poor, the death rate is very high, need to live in the intensive care unit rescue treatment. In the intensive care unit, patients need to monitor blood pressure, respiration, heart rate and urine output, and at the same time, maintain the patients’ water and electrolyte balance. As patients with severe pancreatitis need to fast, they need parenteral nutritional supplementation, and choose drugs to inhibit pancreatic enzyme secretion for treatment, so as not to aggravate the patients’ conditions. After effective treatment, some patients can be saved. If the patient has any discomfort, he should go to the hospital in time for examination and actively cooperate with the doctor’s treatment, do not be careless, so as not to delay the treatment.