Celiac disease is caused by the rupture or obstruction of the thoracic duct for different reasons, resulting in the overflow of celiac fluid into the chest cavity. The thoracic duct is the largest lymphatic duct in the body, with a total length of about 30-40 cm. It then travels up along the right anterior side of the vertebral body and the posterior side of the esophagus and crosses the vertebral body at the fifth thoracic vertebra to the left. It travels up the left side of the vertebral body and esophagus to the neck, returns across the subclavian artery posterior to the carotid sheath and injects into the left venous angle. Thoracic duct rupture is commonly caused by injury, tuberculosis, filariasis, tumor, etc. Its clinical manifestations are stuffiness and shortness of breath, especially obvious when there is a lot of activity or eating more fatty food. In a small amount of celiac disease, there may be no positive signs; in a large amount, the respiratory movement on the affected side is weakened, the percussion is cloudy, and the breath sounds are diminished or absent. Once celiac disease is diagnosed, fasting, blood transfusion, intravenous rehydration, and high nutritional support should be taken immediately. Thoracentesis or closed drainage can completely expand the lung. Those caused by malignant tumor should treat the tumor with radiation. 1/2 patients can be treated conservatively, while the other 1/2 patients need surgery.