Chronic fatigue syndrome (CFS) is a comprehensive systemic syndrome characterized by physical and mental fatigue that develops in healthy people and is often accompanied by symptoms such as swollen and tender lymph nodes, sleep disturbances, physical weakness, low-grade fever, pharyngitis, headache, muscle pain, and depression and anxiety. In the fast-paced, high-stress and changing environment of modern society, it is easy to find that the number of patients with chronic fatigue as the main complaint is increasing day by day. As far as modern medicine is concerned, CFS is mainly regarded as the result of a combination of pathogenic factors. At present, there are many views that its occurrence may be related to viral infection, personality and psychological factors, genetic factors, immune function abnormalities and other factors causing neuroendocrine immune network dysfunction, and its real pathogenesis has not been fully elucidated so far, and further research and exploration are still needed. The formation of chronic fatigue syndrome is the result of a variety of factors, often mixed with various physiological, pathological, psychosocial and other factors in one, because of the differences between individuals, it is believed that in the treatment of specific medication at the same time with the corresponding psychological guidance auxiliary treatment, in order to achieve more satisfactory results. In daily life we pay more attention to the prevention of the disease: 1. Emotionally and morally, it is recommended to keep the mood relaxed and happy, work relaxed and organized. It is recommended that high-risk groups should learn to maintain emotional moderation. The usual attention to expand the mind, keep a normal heart to treat all people and things, learn to get rid of abnormal psychological state in time, but also when the usual attention to develop the habit of empathy, cultivate some good hobbies, transfer the emotional depression, anxiety and other situations. 2, living, for should ensure adequate sleep: modern people are under a lot of pressure in all aspects, which can lead to lack of sleep, and even frequent insomnia phenomenon. Therefore, one of the ways to relieve chronic fatigue is to maintain adequate and good sleep; at the same time should also maintain regular exercise, whether it is jogging, tai chi, massage, yoga, or singing, singing (i.e., keep abdominal breathing), are not lost as a good way to relieve tension and relax the nerves. It is recommended that we should pay attention to personal hygiene in our daily lives, get up and down, and adhere to appropriate exercise. 3, diet, it is recommended that a reasonable diet, balanced and reasonable distribution of protein, carbohydrates, fat ratio in three meals; also recommended more ideal food are: wheat, millet, milk, bread, nori, kelp, yellow fish, apples, bananas, etc.; also stressed that the intake of vitamins and trace elements is of special importance, also according to relevant nutrition research shows that calcium and vitamin A, vitamin B ( especially vitamin B12), vitamin C, vitamin E to maintain normal nerve function, eliminate fatigue, reduce stress, stabilize the nerves have a certain important role. In addition, the Chinese herbal medicine lotus seeds, lily, longan meat, red dates, walnuts, sesame seeds, etc., has the effect of nourishing the heart and tranquilizing the mind, tonic brain puzzle. Pharmacological studies have found that these dual-use foods are rich in tryptophan. Tryptophan is one of the essential amino acids, which can promote the sedation of brain cells, has a calming and hypnotic effect, has a certain effect on improving and relieving the symptoms of chronic fatigue syndrome, and plays a positive role in its conditioning. It is important to use diet as a treatment for chronic fatigue syndrome, because the symptoms of chronic fatigue syndrome are different, so it is especially important to choose the diet for specific symptoms. For example, for those who have obvious gastrointestinal symptoms such as anorexia, nausea, stuffy stomach and abdomen, it is advisable to eat quail, yam, potatoes and other foods that strengthen the spleen and benefit qi and are easy to digest, and avoid eating foods that are cold, fried, hard and stagnant; for those who have symptoms of depression, irritability, depression and anxiety, it is advisable to eat chicken, lean meat, corn, oranges and other products that harmonize the stomach, regulate qi and broaden the chest, avoid eating spicy and stimulating things such as tobacco and alcohol, and eat less For those who suffer from insomnia and dizziness, it is advisable to eat eggs, lotus seeds, jujube, cinnamon and other products that nourish the yin and blood, strengthen the spleen and calm the mind, and avoid over-eating fatty, sweet and thick-tasting products. In addition, we should also pay attention to good eating habits such as eating in moderation, not being too hungry or too full, not being partial to food, and having three meals on time and in quantity. The etiology and pathogenesis of chronic fatigue syndrome (CFS) are different and not conclusive, and the diagnosis and treatment cannot be based on medical history, laboratory tests and physical examination as specific diagnostic criteria. Therefore, in clinical practice, we cannot rely on a single approach to diagnosis and treatment, but should adopt a multi-channel, integrated approach to study this disease, combining Chinese and Western medicine, in view of its complexity. Nowadays, there are many studies in the literature about these diseases, and the theories on the etiology and pathogenesis are becoming more and more mature, but the clarity of these diseases still needs to be further discussed and explored. In our daily life, we need to actively do preventive work, to develop healthy and reasonable behavioral and dietary habits, and to pay attention to humanistic care and psychological guidance.