The terminology does not have a diagnosis of menopausal urticaria, which is an allergic skin disease. The occurrence of urticaria is the result of a combination of internal and external factors. On the internal side, menopausal people are prone to urticaria due to a decline in immune function and resistance to disease. A series of symptoms caused by the decline in the level of sex hormones during menopause, resulting in psychological discomfort; many menopausal people suffer from vegetative nervous system dysfunction, decreased sleep quality, irritability, sensitivity and paranoia. These may affect the body’s immune function. Exogenous factors, urticaria and contact with allergens are very relevant, including pollen, poplar floss, willow floss, dust in the air, allergenic food in the diet, contact with detergent reagents and dyes, and so on. When menopausal people retire, they focus more on family life and outdoor sports, etc., and are more likely to come into contact with some unknown allergens, which can easily cause hives. Menopausal people urticaria and urticaria occurring in other age groups the same principle of treatment, mainly including the external use of glycerine lotion, weak glucocorticoid ointment; when the condition is serious, you can take oral antihistamine drugs. It is recommended to standardize the use of drugs for treatment under the guidance of dermatologists.