Cancer bone metastasis is a process in which cancer cells reach the bone through blood or other pathways, where they grow and destroy normal bone tissue and bone metabolism. The common sites of bone metastasis are pelvic bone, vertebral bone, rib bone, etc. Common manifestations of bone metastasis include: 1. Bone pain: Bone pain in the corresponding area is often the earliest manifestation of bone metastasis, which starts as local intermittent pain and then changes to continuous severe pain, and pressure or collision will increase the degree of pain. On the one hand, it is because the invasion and destruction of bone by tumor is heavier at night, on the other hand, when the patient is quiet at night, the patient’s attention is easily focused on the pain. 2. Fracture: The earliest symptom that may appear in some patients with bone metastasis is fracture. Cancer patients with sudden severe pain or activity dysfunction suggest that fracture may have occurred, which is due to severe bone loss and destruction caused by cancer cells. Ribs and vertebral bones are the most prone to fracture. 3.Other than that, cancer cells destroy bone and cause a large amount of bone calcium to enter the blood in a short time, triggering nausea, vomiting, panic, and even coma. In addition to pain at the fracture site and limitation of motor function, vertebral fracture may even cause paraplegia and urinary and fecal incontinence by compressing the adjacent nerves or the corresponding segment of spinal cord in severe cases. Early detection, close observation, and active treatment are necessary to reduce the occurrence of serious symptoms in patients with bone metastases. How to detect and diagnose bone metastases The preferred method to diagnose bone metastases is ECT whole body bone scan. ECT scan is highly sensitive and can usually detect bone metastases 3-6 months earlier than X-ray. And it can complete the examination of the whole body bones in one test, which is very helpful to detect multiple lesions or even bone metastases without clinical symptoms. Some other examination methods include X-ray examination, CT scan, MRI scan, etc. Treatment of bone metastases Relieving the pain of bone metastases, preventing and controlling fractures, spinal cord compression, hypercalcemia, etc., and improving the quality of life are the goals of treatment of bone metastases. Commonly used methods include pain medications, bisphosphonates, radiation therapy, surgery, anti-cancer therapy, symptomatic support therapy, etc. Doctors will develop a comprehensive treatment plan according to the condition.