Bone metastases are sub-tumors formed when malignant tumors originating from other parts of the body metastasize to the bone through various routes and continue to grow in the bone. Its pain is caused by the metastatic tumor destroying the bone, producing pathological fractures as well as the compression and invasion of nerves by the mass. In recent years, there have been many media reports on cases related to bone metastatic cancer, in which most of the patients think they are suffering from the old back pain again, unaware that the cancer cells in the body start to gnaw on the bones and develop the typical symptom of bone metastasis – pain, and seriously affect the survival quality of cancer patients. In the 3rd Asia Pacific Conference on Interventional Cancer Therapy, Professor Wu Chungen from Department of Radiology, Shanghai Sixth People’s Hospital pointed out that controlling bone metastasis cancer, especially controlling its pain aggravation and deterioration, is an important part of comprehensive interventional cancer therapy. Bone metastasis is a sub-tumor formed when a malignant tumor originating from other parts of the body metastasizes to the bone through various channels and continues to grow in the bone. Its pain is caused by the metastatic tumor destroying the bone, producing pathological fractures as well as the mass compressing and invading nerves. Relieving pain in 85% of patients – percutaneous cementoplasty The principle of intervention for bone metastasis should be firstly to inactivate the tumor, then to restore the function of the bone, fix the fracture as much as possible, or to strengthen the bone, and in addition to protect the adjacent nerves to achieve the effect of pain relief, and finally the comprehensive treatment of systemic intervention. In fact, there are many clinical treatments for bone metastatic cancer, and the radiation community has also used abundant treatments, such as arterial perfusion embolization, cryoablation, radioactive particle implantation, radiofrequency ablation, bone cement plasty, and so on. In particular, Professor Wu Chungen introduced us to percutaneous cementoplasty. Percutaneous cementoplasty, as a derivative of PVP (percutaneous vertebroplasty), is a treatment technique that involves percutaneous puncture of the diseased bone under the guidance of imaging equipment and injection of bone cement into the diseased area under the monitoring of the imaging equipment, thus achieving the treatment purpose of strengthening the bone, inactivating the tumor and relieving pain. It is suitable for weight-bearing bone soluble metastases and non-weight-bearing bone metastases with pain. In other words, this treatment can be used for any metastases with pain. This intervention is not suitable if the patient has severe cardiac, pulmonary, or hepatic insufficiency; severe coagulation disorders, malignancy; irreversible complete spinal cord nerve injury that has occurred for more than 2 months; severe failure, life expectancy less than 3 months, and dislocation of pathological fractures of long bones. The procedure is based on local anesthesia, guided by C-arm fluoroscopy, CT, and DSA machines, and the corresponding puncture needle is selected according to the different bones, featuring minimally invasive and easily accepted by patients, with little or almost no bleeding. The surgical sites include cervical to lumbar spine, pelvis, acetabulum, iliac bone, pubic bone, humerus, sternum, rib cage, scapula, etc. Clinically, the most risky part of this intervention is the upper thoracic spine, where serious complications are likely to occur. Prof. Chun-Gen Wu told us that the efficacy of percutaneous cementoplasty is definite, more than 85% of patients can get effective pain relief, especially the patient’s joint function and bone support function can be better preserved, local tumor can be effectively controlled, and some patients can even reach anatomical cure. In addition, we can add some measures to increase the intensity and efficacy of lesion management before cementing, such as adding radiofrequency ablation or particle implantation, etc.