Patients in hematology suffer from various symptoms such as infection fever, anemia, bleeding, etc. due to various factors such as disease, chemotherapy, bone marrow transplantation, etc. that lead to suppression or even failure of normal bone marrow hematopoiesis, resulting in a decrease in white blood cells, red blood cells, platelets, and consequently various clinical support symptomatic treatments such as infection prevention and control, component blood transfusions, etc. Low white blood cells are common in hematology patients, and even more so, they are as low as zero and persist for a period of time, so the patient’s immunity (resistance) is very poor, and exposure to microorganisms floating in the outside air or an imbalance in the body’s flora, etc., often combine easily with serious infections. Patients with infections not only increase the economic burden, but also may aggravate the disease, and some even delay treatment and endanger their lives due to infection. Authoritative medical statistics show that most of the patients who die from malignant blood diseases die because of infections. Therefore, the prevention and treatment of infection is a fundamental and important topic in hematology. As the saying goes, prevention is better than cure. So what can be done to prevent infections? Here we will briefly explain the prevention of infection in patients with leukopenia. First of all, the exogenous aspect is to prevent the patient from contacting exogenous sources of infection. Due to the low immunity of patients with blood disorders, relatives and friends of patients should reduce visits, especially those suffering from various diseases such as “cold” and “fever” should avoid visiting patients in the hospital, such as telephone visits are appropriate. Relatives should wear masks, hand disinfection and isolation clothing to reduce the chance of foreign infection. In addition, flowers and animals are not allowed to enter the hematology wards to avoid infections caused by various unknown microorganisms, so friends and relatives should keep this in mind. Furthermore, the most important thing is the disinfection of the air in the patient’s space (ward). It is common to install air disinfection machines with ultraviolet light and other functions in wards, which can clean the air in the room; or even to stay in sterile laminar flow beds, which can keep patients in a relatively airtight, sterile and protected environment, and can better protect patients in beds; and 100-level laminar flow wards can provide patients with almost sterile ward space and can provide high-quality total environmental protection. Finally, the prevention of medical source infections such as hand and instrument sterilization of medical and nursing staff and the sterility of drug configuration is also an important part. Secondly, there are various “normal flora” in human body, which have the role of disease prevention, but may also become pathogenic factors when the immunity of the body is low. Blood disease patients themselves should do a good job of wearing masks, washing hands, rinsing their mouths before and after meals, and sitting in the basin after a bowel movement to prevent the invasion of microorganisms outside their own bodies. During the treatment process, medical and nursing staff may make different drug treatment plans to prevent bacterial infections in the body, taking into account the patient’s physical condition and disease status, treatment plans, etc. Communication between doctors and patients should be strengthened, and patients and their families should follow medical advice. For the sudden onset of various uncomfortable symptoms should be timely response to the medical staff, timely and correct symptomatic treatment. The doctor and patient should work together to fight against various infections and eventually cure the disease. The Department of Hematology of Jiangmen Wuyi Hospital of Traditional Chinese Medicine carries out various therapies for treating hematologic diseases including bone marrow transplantation, immune cell therapy, combined chemotherapy and comprehensive Chinese medicine treatment with the support of the hospital. The Department of Hematology attaches great importance to the prevention and control of infection. In terms of infection prevention equipment, it has 4 class 100 laminar flow wards, 5 sterile mobile laminar flow beds, 6 air disinfection machines, 1 ozone disinfection machine and 1 biosafety cabinet, etc. It has achieved the first-class medical environment for infection prevention in the province, and can achieve all-round total environmental protection for patients and reduce exogenous and medical infections as much as possible; coupled with the organic intervention of Chinese medicine The organic intervention of Chinese medicine can effectively adjust the internal environment of patients and reduce the chance of endogenous infection, thus effectively reducing the overall infection rate, providing strong support for the treatment of hematological patients, igniting hope for the cure of the evil hematological disease, and igniting the light of life of patients.