Improvement of drug rash is indicated by darkening and lightening of the rash, flaking, and return of the skin to normal. Drug rash, also called drug dermatitis, is a skin injury caused by drugs into the body, belonging to the adverse reaction of drugs. Common in sulfonamides, antipyretic and analgesic drugs, manifested as itching, pain, skin and mucous membranes appear erythema, blisters, vesicles and other symptoms. Improvement of drug rash is generally manifested as darkening and lightening of the color of the rash, no new rash, flaking and fading of the rash, appearance of normal skin, and gradual reduction of symptoms. The itchiness associated with the onset of drug rash subsides significantly, and other clinical symptoms, such as fever and malaise, will gradually return to normal. Patients with drug rash should stop or change drugs in time, avoid contact with allergic drugs to prevent recurrent attacks of drug rash, and when symptoms of drug rash appear, it is recommended to go to a regular hospital as soon as possible, and standardized treatment under the guidance of the doctor.