Whether or not you can take a vaccine the next day after taking Cephalosporin depends mainly on the health condition of the vaccinated person and the type of vaccine, so it is recommended to consult with the doctor of the vaccination unit, and take the vaccine after evaluating that there is no effect. Cephalosporin belongs to the antibiotic class of drugs, mainly inhibit the reproduction of bacteria, and has no special connection with viruses, and most of the vaccines are mainly against viral infections, so usually there is no adverse pharmacological effect with the vaccine components, and most of the vaccines are often added in a small amount of antibiotics in the preparation process. Generally to take cephalosporin the next day, the concentration of drugs in the body has been reduced to a lower level, usually does not produce a significant effect.1, the health status of the inoculated: an important factor, taking cephalosporin is mostly due to the presence of infectious foci of the body. If not controlled, the patient is in the acute infection period or the existence of fever, usually not suitable for vaccination, but also most of the vaccine contraindications, the need for good control of the disease under the condition of the vaccine and then consider the supplementary vaccine; 2, the type of vaccine: such as live attenuated vaccines, because eating cephalosporins may kill live attenuated live vaccines still have immunogenicity of live viruses, which may affect the effect of vaccination, so you need to wait for the efficacy of cephalexin to play the vaccine, usually 1.5 to 1.5 times. Therefore, it is necessary to wait for the effect of cephalosporin to pass before vaccination, usually 1 week later. In addition, for some special cases, such as being stabbed by sharp instruments or bitten by dogs and cats, because tetanus and rabies are highly fatal diseases, so it is necessary to receive tetanus vaccine or rabies vaccine as a matter of urgency, and at this time, there is no contraindication, and it should be vaccinated as early as possible.