Mycobacteria are generally referred to as mycosis vulvae vaginalis, which is difficult to cure by itself because mycosis vaginalis is characterized by recurrent episodes. For the treatment of mycosis vulvovaginalis, it can be treated by a combination of topical and internal medications. I. Topical medications: 1. douche: such as sodium bicarbonate solution and other drugs, but be careful not to repeatedly douche the vagina for a long time, so as not to disrupt the normal flora and acid-base balance in the vagina, leading to aggravation or recurrence; 2. Topical drugs: for patients with severe vulvar itching, topical ointments can be applied, such as ketoconazole ointment or cream, low concentration glucocorticoid ointment, etc.; 3. Suppositories: in the vulva-vagina After cleaning, put drugs into the vagina, such as mycobacterial suppositories, miconazole suppositories, clotrimazole suppositories, povidone suppositories, dacrynic suppositories, etc., for married women. Second, oral medication: antifungal drugs, such as mycophenolate tablets, fluconazole, amphotericin B and other drugs can be used to kill the mold and help restore local immunity. Pay attention to patients during treatment can not have intercourse, change underwear regularly, underwear in the change down is recommended to use boiling water to scald, sun exposure. Diet should be less sweet and spicy and stimulating food should be prohibited to help recovery from mycosis fungoides. Patients should go to the hospital for regular review and be considered cured when the secretions are tested negative for three consecutive months.