Brain lipoma generally refers to intracranial lipoma, which is a dangerous condition that can cause seizures, increased intracranial pressure, neural tube closure insufficiency, and other discomforts. An intracranial lipoma is a tumor of fatty tissue in the central nervous tissue caused by abnormal embryonic development. Although, intracranial lipoma is a clinically rare form of intracranial tumor disease, it is relatively dangerous. Because, when the intracranial tissues are compressed by the lipoma for a long period of time it may cause epilepsy, with symptoms such as disorientation seizures and twitching of the limbs. Secondly, it can also affect the flow of cerebrospinal fluid circulation, occurring increased intracranial pressure, causing patients to experience headaches, optic nerve edema and other symptoms. Besides, if it is not treated in time, the prognosis is poor, and to a certain extent, it will be combined with such deformities as neural tube closure insufficiency, agenesis of corpus callosum, spina bifida and so on. To summarize, patients with intracranial lipoma need to go to the hospital in time, cooperate with doctors for active treatment, and at the same time, strengthen daily life management to control the development of the disease.