Secretory otitis media is divided into acute and chronic, after standardized treatment in the acute stage, the effusion usually disappears in 1~4 weeks; however, in chronic patients, the condition is prolonged and the time of effusion disappearance is uncertain. The principle of treatment for secretory otitis media is to improve middle ear ventilation and drainage and remove middle ear effusion. In the acute stage, anti-infective, glucocorticoid nasal spray, nasal vasoconstrictor and mucus drainage agents are chosen as the drug treatment, and the effusion can be absorbed in about 1 week and gradually recovered. If the effect of drug treatment is not good or chronic patients, may also need tympanostomy or tube placement, in order to facilitate the reduction of negative pressure in the middle ear and auxiliary drainage, then the recovery time is extended accordingly, some patients need about 4 weeks, or even months to recover. It is recommended that patients actively follow the doctor’s instructions to standardize medication and treatment, so as to avoid the legacy of adhesive otitis media, tympanic sclerosis, cholesterol granuloma and acquired primary middle ear cholesteatoma and other diseases, which will not only increase the difficulty of treatment, but also affect the patient’s quality of life.