What are the clinical features of submandibular gland tumors?

Among the submandibular gland epithelial tumors, benign and malignant account for about 1/2 each. benign ones are all mixed tumors; among malignant ones, adenoid cystic carcinoma is the most common, followed by mucinous epidermis-like carcinoma. Regardless of benign or malignant submandibular gland tumors, the clinical manifestation is the appearance of masses in the submandibular triangle. Benign mixed tumors show painless slow growth with clear circumference and movable masses that are round or can be typically nodular in shape. Malignant tumors are generally faster growing, but there are cases with a history of several years where the mass is hard and often has spontaneous pain or tenderness and symptoms of nerve involvement. If the lingual nerve is involved, tongue pain or tongue numbness may occur, most obvious at the tip of the tongue; if the lingual nerve is involved, tongue paralysis may occur, i.e. tongue movement is limited, and the tip of the tongue is distorted to the affected side when extending the tongue. Adenoid cystic carcinoma of submandibular gland is asymptomatic in early stage and resembles benign tumor. It has a long course and grows slowly. The swelling is of different sizes, flat and round or slightly nodular in shape, and hard in texture. Adenoid cystic carcinoma is relatively mobile at the beginning, but often infiltrates surrounding tissues, resulting in restricted movement. Adenoid cystic carcinoma is especially prone to infiltrate nerves and expand along the nerve fiber bundle, resulting in pain and other symptoms. Mucinous epidermoid carcinoma is usually well circumscribed and may be solid or cystic, and spontaneous ulceration may result in the flow of light tan, mucous fluid. Regional lymph node metastasis can occur in adenocarcinoma and low-differentiated mucous epidermis-like carcinoma. The lymph nodes surrounding the submandibular gland are often invaded by malignant tumors. Submandibular triangle dissection, which removes the submandibular gland together with the tumor and discharges submandibular lymph, is the best treatment for early submandibular malignant tumors.