High tumor marker does not necessarily mean there is tumor. Because high tumor marker is caused by many factors, besides tumor can cause high tumor marker, chronic kidney disease and other diseases can also cause high tumor marker, which need to be differential diagnosis by doctors. Tumor markers are a class of substances that are biosynthesized or released by tumor cells or reactive to cancer by the host in the process of tumorigenesis and proliferation. By analyzing the properties of such substances, they are used as markers to identify tumor cells. However, tumor markers are only auxiliary diagnostic indicators of tumors. If a single tumor marker is found to be high during physical examination or the results of each examination do not change much, the reference role is limited at this time, which may be due to tumors, or may be the effect of chronic kidney disease, because chronic kidney disease may lead to impaired utilization of ferritin, which elevates ferritin levels in the blood, and ferritin levels, which is one of the tumor marker screening routine indicator that can lead to high tumor markers, which may not be a tumor at that time, and the patient does not need to worry too much about it. On the contrary, if tumor markers are found to be dynamically elevated during physical examination, it is necessary to further apply CT examination, ultrasound examination and other methods for diagnosis, especially through pathological examination in order to clarify whether there is a tumor or not. Therefore, high tumor marker does not necessarily mean that there is a tumor, and it needs to be considered from various aspects. It is recommended that patients with high tumor markers should follow the doctor’s instructions and go to the hospital for regular review. Meanwhile, for women, they should not go for examination during menstruation, because examination during menstruation will affect the accuracy of the test results.