Difficulty breathing in anger and tingling of the hands and feet is considered to be a sign of rapid breathing and heartbeat when a person is more emotional in anger. When breathing too fast, the carbon dioxide level can be reduced and the patient will develop respiratory alkalosis. Respiratory alkalosis will stimulate the peripheral nerves of the body, which will cause tingling and chills. As a result of respiratory alkalosis, there will be reflex respiratory distress and hyperventilation. For the occurrence of the above phenomenon, patients are advised to slow down their breathing, breathe deeply, and if necessary, breathe with a mask. At the same time, it is necessary to relieve angry emotions. When the emotions are calmed down and the carbon dioxide level in the body rises by slowing down breathing, the patient’s dyspnea and numbness of the hands and feet can be relieved after correcting respiratory alkalosis.