1. What is the best season to do IVF? In vitro culture conditions such as temperature and humidity, partial pressure of oxygen, partial pressure of carbon dioxide and even nitrogen pressure are all constant at the most suitable conditions for embryo survival. Therefore, IVF is the same no matter what season it is. 2. What are the effects of psychological factors on IVF? In recent years, research in neuroendocrinology has confirmed that the stimulation of adverse mental psychological factors such as long-term worry, depression or fear and anxiety can be transmitted to the brain through the nerves, affecting the function of the thalamus and pituitary gland, hindering the secretion of gonadal hormones and inhibiting ovulation of the ovaries. Meanwhile, emotional factors can also cause spasmodic contraction of the fallopian tubes, hindering the meeting of sperm and eggs, resulting in their inability to combine; abnormal secretion of cervical mucus, making The abnormal secretion of cervical mucus prevents sperm from passing through the uterine cavity and makes it difficult to conceive. Therefore, infertile women should maintain a psychological balance and be optimistic and open-minded, whether in their normal work or in treatment, so that they will not be harmed by the desire for speed. 3.What are the factors that affect male fertility? (1) Smoking and drinking: nicotine and ethanol substances have direct toxicity to the spermatogenic epithelium of the testes, due to the different individual differences in human beings, tolerance is not the same, the degree of harm to each person varies, can cause sperm development malformations to varying degrees, the number of reduced, even if the birth, the fetal malformation rate is much higher than non-smokers. Avoid all smoking and alcohol, especially alcohol (including beer) during the consultation IVF treatment, at least until the wife is pregnant. (2) Wear tight pants and hot baths for a long time: the most suitable environment for sperm production in the testes is 35 to 36°C, 1 to 2°C lower than the normal body temperature. All of the above will increase the local environmental temperature of the scrotum, which will reduce sperm production, reduce the activity rate and increase the malformation rate. (3) Sexual life: too frequent sexual intercourse reduces the sperm content of each ejaculation and the maturity of sperm, which reduces the chance of conception. However, too little intercourse (less than 1 time per month) will lower the metabolism of the testicles, which will also cause a decrease in sperm quality and an increase in dead sperm, and too little sex is not conducive to the metabolism of the woman’s ovaries. (4) Other factors: such as age, environmental pollution, drugs, diet, infection, etc. can cause a decrease in sperm quality. Therefore, before doing IVF, both men and women should pay more attention to rest, correct bad habits, and the male partner should eat more milk and eggs.