Long-term mouth ulcers, mainly related to the following factors: the first point, environmental factors, including the social environment, living environment, work environment, etc., to carry out appropriate self-mindedness adjustment, relieve internal pressure. The second point, immune factors, the decline of their own immunity, resistance, can lead to the frequent occurrence of oral ulcers, can give oral transfer growth factor, usually increase physical exercise, increase resistance, avoid spicy, stimulating diet, eat more vegetables, fruits, etc. The third point, systemic diseases, such as gastric ulcer, duodenal ulcer, ulcerative colitis and other digestive system diseases, are closely related to recurrent oral ulcers. The fourth point, vitamin and trace element causes, mainly the lack of B vitamins and insufficient intake of folic acid or zinc and iron deficiency, can lead to the frequent occurrence of mouth ulcers.