Treatment of chronic atrophic gastritis, sterilization period why after taking drugs, the stomach more difficult? H. pylori bacteria sneak into the stomach and will reside in the gastric mucosa. This group of bad eggs will not only absorb nutrients from the stomach to maintain their livelihood, but also emit a large number of toxins and inflammatory factors, resulting in damage and inflammation of the gastric mucosa. After repeated inflammation and necrosis of the gastric mucosa, the body will experience symptoms such as epigastric distention, epigastric pain, heartburn, poor digestion, constipation, lethargy, and anemia. The process of sterilization, antibiotics and H. pylori fight on the gastric mucosa, which will make the already scarred gastric mucosa more miserable. That is why some patients may feel more uncomfortable such as distension, heartburn and burning pain in the upper abdomen. This is normal and the medication should not be stopped because of mild discomfort. If you have been taking the medicine for a long time (about 8 or 9 days), stopping the medicine once may not have much effect; however, if you interrupt the medicine for several days or take it irregularly during the treatment, then basically this treatment will fail, because this situation can easily lead to bacterial drug resistance. If the bacteria become resistant, the same treatment plan can no longer be used, and the previous treatment will be wasted; moreover, the next treatment will be more troublesome. So, which cases need to stop the medication? A. Allergic rash After taking medication, if a blister or red bumps grow on the skin, sometimes itchy, sometimes not; then this is a rash caused by antibiotic allergy and must be discontinued immediately. Usually the rash will slowly disappear after stopping the medication. Second, the appearance of fever If the patient has fever symptoms after taking the medicine and it persists, you must stop the medicine first, then reduce the fever by physical means, and if necessary, go to the hospital. It is best not to take fever-reducing drugs casually to avoid aggravating the symptoms due to drug interactions. Third, liver function damage During the period of taking medication, liver function tests are done and transaminase levels are found to be elevated. If other causes (such as hepatitis B, C, etc.) are ruled out, then it is drug-related liver damage caused by taking antibiotics, and this situation must also be stopped immediately. Each patient has a different physical condition and reacts differently to different types of antibiotics. So as soon as any of these conditions or other significant discomfort occurs, the medication must be discontinued and a follow-up visit to the hospital must be made, and the doctor will re-evaluate and change the treatment plan.