Patients who have undergone IVF treatment may encounter the following question: It’s been more than two months since I had my eggs retrieved, but why is my period still not coming? Why is the volume of my first period different from before? I didn’t have menstrual pain before, but this time I have my period, why does it hurt so much? Some patients are very nervous and sleepless because of the short-term menstrual disorder after egg retrieval, and even ask themselves: Am I going to have premature ovarian failure? I. What is a normal menstrual cycle? Menstruation is a regular, cyclical uterine bleeding, accompanied by the maturation of ovarian follicles, ovulation, luteal formation and luteal atrophy, which are the results of the regulation of the hypothalamic-pituitary-ovarian axis in the human body. Patients undergoing IVF treatment generally require ovulation promotion therapy in order to obtain as many follicles as possible in a single egg retrieval so that multiple embryos can be formed and multiple embryo transfer opportunities can be obtained. Especially in patients after long protocol pituitary descending, the pituitary gland is in a suppressed state and the hypothalamic-pituitary-ovarian function is not restored immediately after egg retrieval, so there is a short-term menstrual disorder. It is like soldiers who have gone through a great battle and need to rest and adjust before they can enter the next battle. Second, what are the common menstrual regulation programs? 1, relax and exercise: the menstrual cycle is inherently susceptible to mental factors, mood swings, etc. Only when you are well rested can your ovaries be well rested; 2, artificial cycle: hormonal drugs that simulate an artificial cycle can be used to help establish a regular menstrual cycle, which is also beneficial to ovarian rest; 3, appropriate herbal regimen can also be considered.