The main toxic reactions caused by chemotherapy are: (1) myelosuppression, which is initially manifested by a decrease in white blood cells, especially granulocytes. As the dose increases, platelets and red blood cells will also be affected, and aplastic anemia may even occur. Therefore, it is important to check the blood picture regularly during the course of radiotherapy and chemotherapy. (2) Gastrointestinal reactions, such as dry mouth, loss of appetite, nausea, vomiting, abdominal pain or diarrhea, etc. (3) Decreased immune function and resistance to infection. (4) Skin and mucous membrane damage. Such as dry skin, erythema, mouth ulcers, hyperpigmentation, hair loss and nail deformation, etc. (5) Some drugs can cause damage to the nervous system, heart muscle, liver, kidney, lung and other important organs. Chemotherapy not only has many adverse reactions and brings different degrees of damage to the person, but also with the lengthening of the chemotherapy course, the sensitivity of chemotherapy gets worse and worse, and even produces drug resistance, and the therapeutic effect will be greatly reduced. How can we reduce and eliminate the toxic reactions of chemotherapy, but also improve the therapeutic effect, to help patients through chemotherapy this hurdle? First of all, we should adhere to the center of “human-centered”, that is, we must change the misconception of “tumor” as the center of tumor treatment in the past, and develop human-centered treatment plans, so that patients can live with tumor for a long time. In addition to the application of chemotherapy drugs, there are also drugs for the prevention of common toxic side effects, which can be combined with some traditional Chinese medicine, psychotherapy and food therapy. This can not only reduce and eliminate toxic reactions, but also strongly improve the effect of chemotherapy.