What are the common freckles, cheek brownish nevi and melasma on our face? How to distinguish them? How to get rid of freckles effectively? Freckles are isolated, non-fused brown pigmentation spots commonly found on exposed areas, which can be triggered and aggravated by sunlight. It is an autosomal dominant disease that appears in early childhood and often increases in adolescence. It is commonly found on the nose and cheeks of female face, with a diameter of 3-5mm, round, oval and polygonal lesions, irregularly bordered light brown to dark brown spots with clear boundaries, isolated and non-fused, sparsely and unevenly distributed, with light color in winter and heavy in summer. Our treatment includes strong pulsed light OPT, Q-switch (532nm, 755nm) laser, oral vitamin C and E and external vitamin C and E essence and sunscreen. Melasma, called liver spot, is a light brown to dark brown pigmented spot on the face (cheek, cheek, nose, forehead and chin), often symmetrical and butterfly-shaped, without conscious symptoms. The etiology is still unknown, currently it is thought that it may be related to pregnancy, oral contraceptives, endocrine, certain drugs, cosmetics, genetics, liver disease and ultraviolet light. Our treatment includes large spot low energy density Q-switched Nd:YAG 1064nm laser, 1540nm non-ablative fractional laser, pulsed intense light OPT and other laser treatments and fruit acid revitalization treatment, together with oral and external application of drugs that promote melanin metabolism or inhibit the secretion of complexinase, which can improve to a greater extent. Zygomatic nevus is a dark gray spot pigmentation symmetrically distributed in the zygomatic area, with the majority on the zygomatic area and a few on the eyelids and nasal flank area, which is grayish brown, dark gray or dark brown pigmentation with a diameter of about 1-5mm, round, oval or misshapen, with clear boundaries, and the number varies from several to dozens, with an average of 10-20. The rash is not raised or sunken on the skin surface, and most of them are distributed bilaterally and symmetrically. There is no damage to the eye or oral mucosa. The patient has no conscious symptoms. The pathogenesis is that during embryonic development, melanocytes migrate from the neural ridge to the epidermis and for some reason do not pass through the epidermal-dermal junction and remain in the dermis and form lesions.