The difference between gastritis and duodenal ulcer is as follows: 1. The difference in location, gastritis is a chronic inflammatory lesion that occurs in the stomach cavity, and duodenal ulcer is a chronic ulcer that occurs in the duodenum. 2. The difference in foci, gastritis refers to a chronic inflammatory lesion that occurs in the mucosa of the stomach, but the inflammatory lesion is only confined to the mucosal layer of the stomach. If a patient with chronic gastritis mostly shows symptoms of indigestion, drugs to help digestion can be given. For the treatment of duodenal ulcer, it is required to give regular anti-ulcer drugs, is the choice of acid-suppressing drugs combined with bismuth, if the duodenal ulcer is caused by H. pylori infection, also need to give regular eradication of H. pylori treatment.