Cough asthma, also known as cough variant asthma, is a specific type of asthma in which chronic cough is the main or only clinical manifestation. At the onset of bronchial asthma, about 5%-6% of them have persistent cough as the main symptom, mostly occurring at night or in the early morning, often as an irritating cough, which is often misdiagnosed as bronchitis at this time. In recent years, this problem has attracted the attention of many scholars at home and abroad, and it has been found that asthma accounts for 24% of the single causes of chronic cough, ranking 2nd, while 28% of asthma patients have cough as the only clinical symptom. Clinical manifestations In adults presenting with cough asthma, the age of onset is higher than in typical asthma, with approximately 13% of patients older than 50 years and more common in middle-aged women. In childhood, cough may be the only symptom of asthma or even a precursor to the development of bronchial asthma. There is mostly a clearer family history of allergies or a history of allergic diseases in other areas, such as allergic rhinitis and eczema. Most of the attacks are seasonal, with spring and autumn being the most common. The clinical manifestations are mainly long-term persistent dry cough, often induced after exercise, cold air inhalation, upper respiratory tract infection, intensified at night or in the early morning, no croup on physical examination, lung function impairment between normal and typical asthma, skin allergen test can be positive. A positive bronchial excitation test, when positive, can be followed by an irritating cough similar to that of the onset, suggesting the presence of airway hyperresponsiveness; a positive reversibility test for airway obstruction. General cough suppressants and antibiotic therapy are ineffective and may be relieved with antihistamines, β2-agonists, theophyllines, or adrenocorticosteroids.