We have talked earlier about burnt needle robbing for meridian disease, pain as transfusion, needle selection for meridian disease, and some treatments of acupuncture, and next we will discuss the multi-needle method for meridian disease with pain as transfusion. The pain point of pain as transfusion, i.e. pain transfusion, is an acupuncture point, which generally depends on the disease, it has neither a specific point name nor a fixed location, it is a pressure point or other pathological reaction point as the acupuncture treatment point. It has some reference value in disease diagnosis. Pain transmission reflects two major systemic diseases of the human organism, i.e. visceral diseases and meridian diseases, which are reflected in the form of pain transmission and are realized through the conduction of meridians. The meridians are internally connected to the internal organs, externally connected to the limbs and joints, communicating with the internal and external up and down, transporting qi and blood nutrition to the whole body. The transmission of disease from the surface to the interior is also through the channels of the meridians. Therefore, the A-Yi point is the best stimulation point for treating diseases and also the response point for diseases, and is widely used in clinical practice for diagnosis and treatment. Pain response points for visceral diseases are mostly manifested in a punctiform form, mostly below the elbows and knees, on the trunk and between the spine, and their pain points are limited in scope, mostly residing at or near the corresponding meridian points. On the other hand, the pain reaction points of meridian diseases may occur in all places of the body where there are tendons and flesh, and the pain location is not necessarily limited to a narrow point, but sometimes a surface of variable scope, the scope of which is related to the depth of the lesion and the size of the lesion. In other words, the painful points of visceral diseases are the reflection of visceral diseases on the surface of the body, and the painful points of meridian tendon diseases are the reaction points of foci of meridian tendon diseases. In the treatment of acupuncture, the pain points of visceral diseases are acupuncture points or related points with milli needles, while the pain points of meridian tendon diseases should choose thicker or edged needles, because the pain points of meridian tendon diseases sometimes have a large pain surface, single needle is difficult to work, in the acupuncture treatment, consider the method of multi-needle acupuncture, or multi-directional acupuncture method, the pain surface is small needle less, the pain surface is large needle more, depending on its specific situation, can be used to enter a needle into a needle into a needle of the evening acupuncture The pain surface is small, but the pain surface is large, depending on the specific situation, the stabbing method can be used respectively, i.e., multi-directional penetrating stabbing after entering the needle. The clinical application of multi-acupuncture and multi-directional acupuncture in the Nei Jing should focus on acupuncture treatment for painful meridian diseases.