Mastocytosis is a general term for a group of diseases that are characterized by pathological changes of hyperplasia of the alveoli, ductal epithelium and connective tissue of the breast, and its incidence accounts for 80-90% of women of reproductive age and 75% of all breast diseases. Since breast hyperplasia is one of the risk factors associated with breast cancer, it is important to understand its causes, occurrence and development, and to actively and effectively prevent and treat it in order to reduce the risk of breast cancer. The cause of mastocytosis is not yet determined, but most scholars believe that it is related to ovarian endocrine imbalance. Elevated estrogen level and decreased progesterone level or imbalance of estrogen and progesterone ratio can lead to excessive glandular hyperplasia or incomplete restoration, tissue structure disorder, causing pain and forming nodules or cysts. Mental tension, high psychological stress, irregular life and high-fat diet can play a part in promoting this. (2) Clinical manifestations of breast hyperplasia (1) Breast pain: often swelling or stabbing pain, on one side or both sides, heavily radiating to the ipsilateral armpit or shoulder and back, mostly appearing or aggravated several days before menstruation, alleviating or disappearing after menstruation, which can fluctuate with emotional changes, exertion and weather changes. (2) Breast lumps: Lumps may occur unilaterally or bilaterally, single or multiple, mostly in the upper outer quadrant. They may be lamellar, nodular or striated, with lamellar lumps being the most common. The borders are unclear, medium or slightly hard, with tenderness and no adhesions to the surrounding area, and they also have the characteristic of changing with the menstrual cycle, i.e. increasing in size and hardening before menstruation and shrinking and softening after menstruation. (3) Nipple overflow: A few patients can have it, and the overflow is mostly yellowish or pale milky white. Bloody or coffee-colored overflow should be alert. 3.The relationship between mastocytosis and breast cancer Whether mastocytosis is cancerous or not is still inconclusive. Studies have shown that the cancer rate of the disease is about 2-3%, and the risk of cancer with atypical hyperplasia is 3-5 times greater than that of the general population. When the nipple overflow is bloody or plasma, and the limited glandular thickening does not change with the menstrual cycle, precancerous or cancerous lesions should be considered. 4, treatment of breast hyperplasia (1) change of life behavior: keep a relaxed mood, avoid anger, strain; moderate physical exercise, weight loss; quit smoking and alcohol; low-fat, light diet, etc. (2) Medication: Western medicine includes vitamins (B6, E, A), iodine and sex hormones (triamcinolone, danazol, cryptotin, testosterone, progesterone, etc.). Chinese medicine treatment is to promote the flow of qi and blood, soften the hardness and disperse the nodules, commonly used are breast dissipation capsule, Yanlu breast health tablet, prolotherapy and Xiaojin pill. (3) Combination of Chinese and Western medicine treatment – “three talents therapy”: “three talents with acupuncture points comprehensive therapy” is a new method of combination of Chinese and Western medicine treatment of benign breast diseases developed in recent years. Research shows that the total effective rate of “Sancai Therapy” with oral treatment of mammary gland hyperplasia is 97.5%, which is significantly better than the control group treated with Prosperity San alone. The treatment with this method is 40-60 minutes each time, 10-15 times per course, which can quickly relieve pain and improve the size and hardness of lumps, and is an effective method to treat breast hyperplasia and reduce the risk of breast cancer, which is worth promoting.