Patients with sore feet in the middle of the night, the following causes are common: first, cold feet: the surrounding environment is too cold, during sleep without attention to foot warmth, easy to produce cold feet, the feet will appear obvious blood circulation disorders, muscle tension, the patient will show clinical symptoms of sore feet. Through hot compress and massage treatment, the clinical symptoms can be relieved. Second, disease factors: patients suffering from long-term diabetes, and poor blood sugar control, will cause peripheral neuropathy and peripheral vascular blood disorders, will also have the clinical symptoms of sore feet in the middle of the night, and not easy to relieve, the persistence will affect normal sleep, the symptoms will recur, blood sugar presents obvious instability. The appearance of sore feet in the middle of the night must be paid great attention to, early diagnosis and early treatment, which can make the clinical symptoms get fast relief. If the treatment is delayed, it will make the symptoms persist.