Healthy sleep is an essential part of our healthy life, and only with sufficient healthy and reasonable sleep can we have sufficient energy to work and live. This is why healthy sleep is so effective in the treatment of most diseases and is an essential part of the treatment of various diseases. Sleep has a significant impact on epilepsy, and the two interact and are closely related. Epileptic seizures have a significant impact on sleep structure and sleep efficiency, and similarly sleep-wake cycles affect seizures. At least 25% of seizures in the epilepsy population are sleep-related. Sleep-related epilepsy is defined as epilepsy in which seizures occur during sleep or are more likely to occur during sleep. Regardless of the cause of epilepsy, sleep disorders such as irregular sleep-wake cycles or sleep deprivation can be a contributing factor to sleep-related epilepsy. A significant proportion of patients with sleep-associated epilepsy may have psychological problems. On the one hand, the onset of epilepsy may be related to the patient’s quality and personality; on the other hand, clinical observation also proves that mental stimulation is often a contributing factor to epilepsy, and various stressful stimuli can indeed induce seizures. In addition, patients with epilepsy often lose confidence in treatment due to the lingering disease, resulting in low self-esteem and emotional depression; coupled with adverse stimuli from society and family, all of which may lead to serious psychological disorders. Therefore, it is necessary to provide psychological treatment for epilepsy patients. In addition, for children with epilepsy, special attention should be paid to ensure adequate sleep, do not stay up late at night, and develop a good habit of sleeping on time every day, because lack of sleep is a common trigger for seizures. If possible, it is best for children with epilepsy to take a nap at noon. In addition, it is important to pay attention to sleep posture and develop a supine or side-lying sleep posture, avoiding a prone sleeping position as much as possible, especially for children with frequent nighttime seizures. In the case of epilepsy, sleep disorders can lower the seizure threshold and may cause an increase in the number of seizures, so the necessary medication should be administered for sleep disorders. Sedative-hypnotic medications can both treat certain types of sleep disorders and synergistically treat sleep disorders in patients with epilepsy.