The success of IVF is not limited to the embryos hitting the ground, but bringing home a healthy baby. Many people feel that the egg retrieval and transfer procedures are crucial in IVF treatment, but this is not the case. The egg retrieval and transfer procedures can be mastered through repetition, just as learning to swim and ride a bike. So what are the most crucial factors for IVF success? 1. Good quality embryos —- High quality eggs and sperm The prerequisite for obtaining good quality embryos is to obtain good quality eggs and sperm. The quality of the eggs is firstly related to age. In general, the younger the egg the better the quality. The ability to obtain the best number and quality of eggs for a given age of a woman is again largely dependent on the ovulation program. Different infertile women with different age, ovarian reserve, body weight, and response to medications have different ovulation regimens, and different types and dosages of medications used for ovulation. Our center’s individualized ovulation regimen for infertile women means that each infertile woman is given a personalized ovulation regimen based on her own special characteristics to achieve an optimal ovulation regimen outcome. Sperm quality seems to be more affected by a man’s lifestyle, disease or genetics. Unhealthy lifestyles such as late nights, obesity, smoking and alcohol abuse, and hot work environments will reduce sperm quality. Certain diseases such as chromosomal abnormalities, Y chromosome segment deletions, varicocele, rubella or juvenile mumps will cause male infertility. We currently assess male fertility by sperm count, morphology, viability and sperm DNA fragmentation index (DFI), of which DFI has the most predictive value and correlates with embryonic developmental potential. For male patients undergoing IVF, we routinely assess these indicators and find that many infertile men have a high sperm DFI. When treated with lifestyle modifications combined with medication, most men’s DFI indicators can be decreased, which is quite beneficial for fertilization and embryo development. 2.Good endometrium —– suitable hotbed for embryo planting Successful embryo implantation is the result of a harmonious dialog between the embryo and the endometrium. There are already good quality embryos, our focus is on the endometrium. If the endometrium is of good thickness and morphology and has a rich blood flow, the success rate is higher after transferring a quality embryo. In what cases is the endometrium unsuitable for embryo implantation? Diseases of the endometrium, such as uterine polyps, submucous fibroids, endometrial hyperplasia, endometritis, and uterine adhesions, may affect the embryo’s ability to find suitable soil for implantation. In addition, thin endometrium, poor endometrial blood flow, tubal effusion, and asynchrony between endometrium and embryo development may also affect embryo implantation. When this occurs, embryo transfer should be canceled and endometrial pathology should be treated first. If there are organic lesions in the endometrium, these should be removed by surgical or pharmacologic treatment prior to transfer. If the endometrium is very thin and drugs cannot thicken it, the chances of conception can be increased by improving the blood flow to the endometrium. 3, healthy body internal environment —- create a good environment for fetal growth and development Embryo implantation into the uterine lining is the first step to a successful pregnancy. If you want to get a healthy baby, you have to let the fetus grow and develop healthily in the uterus. The baby’s nutrients and oxygen come from the mother’s blood exchange, so it is very important for the mother-to-be to have a healthy and balanced body for the baby’s development. Some of the more common disorders of the internal environment in women of childbearing age include hyperprolactinemia, hyperandrogenemia, abnormal thyroid function, autoimmune disorders, abnormal coagulation, metabolic abnormalities, and bacterial infections. These abnormalities in turn seem to be inextricably linked to infertility, spontaneous abortion or embryo termination. Correcting these abnormalities through lifestyle changes and medication before embryo transfer to provide a healthy and balanced developmental environment for the embryo will promote the healthy growth of the baby and reduce the occurrence of complications during pregnancy and childbirth. In addition to being in good physical condition, it is also very important to be in good psychological or mental condition. Adverse emotions such as tension and anxiety may affect the development of follicles, and the body under stress may secrete certain harmful hormones that further disturb the homeostasis of the body. Therefore, people should keep a relatively relaxed and happy mind during the treatment process and believe that they can get pregnant. Do something you like in your spare time to divert your attention. When you have questions during the treatment, don’t hold them in, we are always at the clinic and you can talk to us at any time. The embryo is equivalent to the seed, the uterine lining is equivalent to the soil, and the internal environment of the woman’s body is the sunshine and rain, when these aspects are good, the desire to carry a healthy child home will certainly be realized!