Many women put their infertility treatment on IVF technology, however, the cruelty is from the clinical data, the success rate of IVF for older women over 45 years old is very low, or the probability of miscarriage after pregnancy is also elevated. Why are older women doing IVF prone to failure? Failure of IVF in older women: Poor quality of eggs or sperm, resulting in poor quality of the embryo itself is the main cause. The optimal age for women to have children is 25-29 years old. The success rate of IVF is higher at this stage. Women over 35 years of age are considered to be of advanced age, where fertility plummets and the number of eggs available in the ovaries decreases significantly. Therefore, doctors will increase the dosage of drugs when promoting ovulation, but the ovaries of elderly women respond poorly to the ovulation drugs, or there may be no growth of follicles after using the drugs and terminate the procedure halfway; even if the ovarian response of some of the patients is still OK, but the overall number of follicles is low and the quality is poor, and there may be fertilization abnormality, poor development of the embryos, and there are no good embryos to be transferred. A small number of good embryos may be harvested in a proportion of patients, but the endometrium of older women becomes less receptive, with a lower success rate after later embryo transfer or a higher rate of miscarriage after pregnancy. Thus IVF success rates decline sharply with age. It is an unchangeable fact that advanced age causes women’s ovarian function to decline and the quality of eggs will get worse and worse. Environmental pollution, heavy life and work pressure, unhealthy living habits, etc., make the ovarian function of elderly women “worse”, thus making it more difficult for them to have children. Women with heavy psychological pressure, their endocrine will be affected, the blood vessels are in a state of contraction for a long time, affecting the uterus, ovary local blood flow, and nervous system tension will make some nerve mediators release abnormally, resulting in uterus, fallopian tube muscle contraction disorders, resulting in the embryo can not land on the bed and lead to treatment failure. Therefore, it is very important to relieve psychological pressure, communicate between doctors and patients, and both couples sympathize and encourage each other. Therefore, too much tension before and after implantation of elderly women can also cause implantation failure. It seems that it is quite common for older women to fail IVF, so before doing IVF, you should be well prepared psychologically and physically, and cooperate with the doctor for active treatment, and work together to usher in a good pregnancy.