In the clinical work of otorhinolaryngology, maxillary sinus diseases are very common, such as maxillary sinus cyst, maxillary sinus polyp, maxillary sinus mycosis, maxillary sinus papilloma, etc. The treatment about maxillary sinus diseases mostly needs to be treated by maxillary sinus radical surgery before the nasal endoscopic surgery is carried out, although maxillary sinus radical surgery has been carried out for more than 100 years, but after the surgery, it can cause many complications such as facial numbness, swelling, tearing, prolonged dental numbness, postoperative complications such as maxillary sinus cysts, and even zygomatic arch fractures. Many otorhinolaryngologists are trying to improve the maxillary sinus surgery, and in the late 1990s, nasal endoscopic surgery was widely carried out in China, so that most of the patients with maxillary sinus disease have achieved good treatment results after the expansion of the maxillary sinus opening, but there are still many patients who cannot be treated well despite the expansion of the maxillary sinus opening, and for this reason, we have carried out a nasal endoscopic approach through the lateral nasal cavity For this reason, we carried out the treatment of refractory benign maxillary sinus lesions through the lateral nasal incision approach under nasal endoscopy. In the past year, we have performed this new procedure for many patients under general or local anesthesia, starting with an anterolateral incision of the inferior turbinate, dissecting out the nasolacrimal duct and forming a nasolacrimal duct-inferior turbinate flap, and then moving inward to form a maxillary sinus approach, followed by complete removal of the maxillary sinus lesion under direct nasal endoscopy, and finally resetting the nasolacrimal duct-inferior turbinate mucosal flap and, if necessary, performing an inferior nasal opening. Postoperative pathological exclusion was performed in all patients. As a result, all the patients used were pathologically confirmed as benign lesions after surgery, and malignant tumors were excluded. The evaluation was performed at 3 months after surgery, and 10 cases were cured and 3 cases improved. There were no complications such as cheek numbness, tearing, intraorbital hemorrhage, visual impairment, or cerebral fluid nasal leakage after follow-up. The nasal endoscopic lateral nasal wall incision approach to the maxillary sinus had a wide field of view, which facilitated the complete removal of the entire maxillary sinus cavity lesion and preserved the nasolacrimal duct and inferior turbinate, with satisfactory clinical results.