Susceptibility and predisposition factors for tuberculosis refer to factors that predispose or promote tuberculosis infection, morbidity, and disease. Understanding these factors helps to improve the understanding of the etiology, pathogenesis and prevalence of TB. They are important for the clinical diagnosis and treatment of tuberculosis as well as for prevention and control. 1, genetic factors: Studies have shown that the proportion of identical twins suffering from tuberculosis is much higher than that of dizygotic twins, proving that genetic factors have a definite impact on tuberculosis patients. 2, age: China’s three flow survey results show that the prevalence rate under 20 years of age increases rapidly with age, and then grows slowly to reach a peak at the age of 70, and then decreases. 3, gender: the prevalence rate before the age of 20 years is higher in women than in men, and then higher in men than in women, showing that age and gender have a definite impact on the onset of tuberculosis and disease. Postpartum women are prone to TB, especially hematogenous TB and tuberculosis, and are easily confused by symptoms of puerperal fever and delayed diagnosis. 4, occupation: certain occupations are closely related to tuberculosis. For example, silicosis is prevalent in the dust industry and silicosis patients are susceptible to tuberculosis. The prevalence of tuberculosis is 10 times higher in those who are negative for long-term nursing than in those who are positive. 5, drugs and tuberculosis: corticosteroids, immunosuppressants often cause latent tuberculosis, such as: asthma long-term use of hormones, organ transplantation long-term application of hormones and immunosuppressants, malignant tumor surgery and chemotherapy is such. In recent years, these cases have increased. Diabetes, liver and kidney disease, post-gastrectomy, influenza, measles, whooping cough infection, are prone to tuberculosis; malignant tumors affecting lymphocyte immunity, such as lymphoma, leukemia, AIDS, etc. Since the mid-1980s, the prevalence of tuberculosis in the United States has increased, 1/3 of which is attributable to the AIDS epidemic. 6, malnutrition, overexertion to reduce resistance to tuberculosis is also susceptible to TB. 7, itinerant population, refugees, immigrants: due to unstable life, poor nutrition, fatigue, crowded living and easy infection, disease. 8, poor social environment factors: such as poverty, war, famine, natural disasters, etc.