The following herbal medicines have caused liver damage in animals to varying degrees in toxicological tests: mulberry leaf, seasonal green, ground elm, fish vine, daylily root, clove, neem seed, neem bark, smallpox powder, big white top grass, celery seed, stinkweed, wild lily, light powder, seaweed, spotted vetch, castor seed. The Chinese herbal medicines that can cause liver damage are: Dioscorea (Dioscorea dioscorea), Huang Yao Zi, Lei Gong Vine, Qian Li Guang, Cang Er Zi, Neem, Guan Zong, Coriander, Tong Tribulus terrestris, Tu Zhi Zhi Zhi, Hooked, Mugwort, Da Bai Ding Cao, Ricinus communis, Shepherd’s Purse, Yi Ye Qiu Alkali, Garcinia, Da Feng Zi, Acacia, Chang Shan, Wang Jiang Nan Zi, Xi Shu. Some topical herbs can cause different degrees of liver damage when taken by mistake, such as fish guts, fish vine, sea hare, andrographis, raw cotton seed oil, tung seeds and tung oil, etc. Aristolochic acid-containing herbal medicines: Aristolochia genus: Big Leaf Greenwood, Yunnan Aristolochia, Southwood, Pipe Southwood, Three Tube Pipe, Pod Leaf Aristolochia, Vermilion Lotus, Aristolochia, Tian Xian Vine, Greenwood, Gourd Leaf Aristolochia, Guang Fangji, Tongcheng Tiger, Hainan Aristolochia, Hanzhong Fangji, Vine Xiang, South Yue Aristolochia, Concave Vein Aristolochia, Huai Tong, Back Snake Sheng, Pipe Southwood, Guan Mu Tong, Seeking Bone Wind, Leather Leaf Aristolochia, False Big Potato, Butterfly Dark Fade, White Vermilion Butterfly dark elimination, white vermilion lotus, forced blood thunder, white gold fruit olive, small southern wood incense. The genus Hesperus: earth horsetail, large horsetail, miscellaneous horsetail, Du Heng, horsetail, golden earring, earth golden earring, Ugnion grass, flower-faced horsetail, Taitung horsetail. It is important to note that drugs containing aristolochic acid are not the only ones that cause kidney damage. A large number of modern clinical studies have also identified a group of Chinese medicines that can produce different degrees of nephrotoxicity with long-term or excessive application, and there are currently 68 of them. According to their sources, these long-term or over-application nephrotoxic herbal medicines can be divided into three categories, which are commonly used as follows: 1. Plant-based herbal medicines such as Mouton, Houpu, Fangji, Zelenia, Chaihu, Cao Wu, Coriander, Gansui, Ba Dou, Aloe, Bitter Ginseng, Lei Gong Vine, Yimu Cao, Junzi, Neem Bark, Cang Er Zi, Petunia, Aristolochia, Smallpox, Thornbush, Da Qing Ye, Shan Ci mushroom, Qian Li Guang, Ziziphus, Phyllostachys, Phyllostachys, Phyllostachys. 2. Animal herbal medicines such as fish gall, snake gall, zebra, centipede, seahorse, red maiden, etc. 3. Mineral herbs: arsenic-containing herbs (e.g. Xiong Huang, Arsenicum, Arsenicum, Red Alum); mercury-containing herbs (Cinnabar, Light Powder, Mercury); lead-containing herbs (Lead Dan) and Alum, etc. Clinical use of drugs, in terms of dose, preparation, combination, decoction method should pay attention to, like the use of heavy generous should be particularly cautious.