To prevent osteoporosis, in addition to calcium supplementation, breast cancer patients should also pay attention to the following:
- Outdoor exercise
Medium-intensity weight-bearing exercise such as walking and jogging is good for maintaining bone strength, with no less than 30 minutes of exercise recommended daily. And the ultraviolet light from the sun helps the skin synthesize vitamin D. More sunlight is better for calcium absorption.
- Osteotriol
Osteotriol is one of the active substances produced after the degradation of vitamin D3, and its main role is to promote the absorption of calcium in the intestine and to promote the calcification of bone. There are different sizes of osteopontinol, such as injections, pills and capsules, which can be ingested together with calcium, and you need to consult your doctor for the exact dosage.
- Diphosphonate drugs
Bisphosphonates are effective inhibitors of osteoclasts, inhibiting bone resorption and increasing bone mass, promoting bone health, and relieving bone pain associated with bone metastases from breast cancer. One of the most common domestic bisphosphonates is zoledronic acid, which is recommended every 12 months for patients at high risk for osteoporosis with a T value (bone mineral density value) <-2.5.
- Disulfiramab
Dixumab is a human IgG2 monoclonal antibody that inhibits the activity of osteoclasts. Compared to zoledronic acid, disulfiramab has fewer side effects, is simple to use, and is effective in boosting bone density. The two drugs, disulfiramab and zoledronic acid, should not be used together, but one of the two drugs should be used.