Reflux esophagitis refers to inflammatory erosions and ulcers and fibrosis of the esophageal mucosa caused by the reflux of gastric and/or duodenal contents into the esophagus, which is known as gastroesophageal reflux disease. Clinical manifestations are mainly heartburn, acid reflux retrosternal pain, and some patients may develop extraesophageal symptoms, such as chronic cough, etc. Severe cases often affect the patient’s sleep and life treatment, long-term reflux can damage the esophageal mucosa damage, and even cause tumors of the esophagus to occur. The correct treatment of reflux esophagitis: (a) general life-saving lack of treatment diet should be a small number of meals should not be too full; avoid tobacco, alcohol, coffee, chocolate, acid food and excess fat; avoid lying down immediately after meals; bed head elevated ~ cm when lying trouser belt should not be too tight to avoid such a variety of cause abdominal pressure too high state (b) promote the emptying of the esophagus and stomach dopamine antagonists such drugs out of the clinic can promote the emptying of the esophageal office to increase the lower esophagus Tension of such laboratory drugs include metoclopramide (metclopramide gastric renformation) and domperidone (domperidone morpholine) are ~ mg per day ~ times before bed and meals, the former if too large a dose or long-term use can lead to extrapyramidal neurological symptoms, so elderly patients are often used with caution; the latter long-term use can also lead to hyperprolactinemia, lactation and amenorrhea, such as breast enlargement Adverse reactions cisapride releases acetylcholine through the postganglionic nerve of the intestinal plexus to promote esophageal gastric peristalsis and emptying, thus reducing gastroesophageal reflux ~mg per day ~ days few adverse reactions cholinergic ura choline (bethanechol) can increase the tension of the LES to promote esophageal contraction to speed up the emptying of acidic food in the esophagus to improve the symptoms of the doctor every two weeks This mouth can stimulate the secretion of gastric acid ~ times a day and should be taken with caution for a long time (c) reduce gastric acid ① acid control agents can neutralize gastric acid and thus reduce the activity of pepsin to reduce the damage of acidic gastric contents to the esophageal mucosa alkaline level of the drug itself also has the effect of increasing the tension of the LES very good aluminum hydroxide gel ~ ml and magnesium oxide g ~ times a day alginic acid foam ( garisconalginate) contains alginate and sodium alginate and acid producing agent can float on the surface of gastric contents to stop the reflux of gastric contents ② histamine H receptor antagonists metacycline (cimetidine) furosemide (ranitidine) and famotidine (famotidine) can be used at doses of mg~/d; mg times/d and mg/d respectively The other drugs in this class can strongly inhibit the secretion of gastric acid and improve acid reflux in the gastroesophagus, and the underlying symptoms can be increased to ~ times if they do not improve. The former mg/d and the latter mg/d can improve the symptoms too little (d) Combination of drugs The combination of drugs to promote esophageal gastric emptying and acid suppressants has a synergistic effect Tuesday can promote the healing of esophagitis can also use dopamine antagonists or cisapride in combination with histamine H receptor antagonists or proton pump inhibitors The disease in the use of good improvement and after discontinuation of drugs because of its LES tension failed to get medical attention at all (v) Endoscopic treatment: including radiofrequency therapy, endoscopic ligation suture law, endoscopic direct vision folding, etc. Currently, these methods are only applicable to non-erosive esophagitis, and they are all experimental treatments. Experimental treatment, the lack of small sample studies, so the current value of the application in the clinic is not clear, endoscopic treatment still need problems need to be solved. (E) surgery did not come to the cost of treatment Not guilty mainly applies to esophageal scar stenosis (feasible dilatation or surgical sentence corrective surgery) and internal time treatment is ineffective repeated bleeding repeated concurrent pneumonia and other symptoms of the condition But the treatment of surgery also has a certain risk and a certain failure rate. One group of experimental studies showed that there was no significant difference in the long-term results between patients treated with medical drugs and those treated with surgery. In conclusion, the current treatment of reflux esophagitis is still the first choice of medical medication, and the vast majority of patients can be relieved by regular medication.