Postoperative complications of craniosynostosis can affect the prognosis of patients. Depending on the condition of each individual, the level of the surgeon, and the method of surgery, each person will have different postoperative complications. These postoperative complications include increased intracranial pressure, intracranial hemorrhage, infection, hydrocephalus, cerebrospinal fluid leakage, cerebral ischemia, coagulation dysfunction, and metabolic disorders. One of the most common post-operative complications is the manifestation of dizziness and headache, but usually, they will improve in seven days and can be relieved by oral administration of relevant medications, such as loxoprofen and acetaminophen, if necessary. Other people may experience numbness and weakness of the limbs and speech dysfunction. Hemorrhagic shock can be caused by the craniotomy process of supratentorial meningioma surgery. The blurring of the surgical field due to bleeding during intracranial operations and the tendency to accidentally injure adjacent tissues and structures, especially unrelated arteries and draining veins, are the main causes of postoperative functional deficits. Some people also have the possibility of residual epilepsy, which can be treated with oral medications, or if the pharmacological approach is ineffective, with craniotomy and neuromodulation techniques. Depending on the circumstances, some people may develop hydrocephalus, subdural fluid, etc. This is usually decompressive hydrocephalus after tumor removal. Some postoperative complications are mild and can be cured, while some are more serious and can even cause the death of the patient. However, many postoperative complications can be prevented and avoided if treated carefully.