There are 3 basic management strategies for patients with pulmonary nodules: (1) surgical treatment, (2) non-surgical biopsy, and (3) close follow-up with serial CT scans. Monitoring of lesion volume changes is recommended during follow-up, and lung nodules that remain stable in volume for 2 years are indicative of benign lesions, as evidence suggests that volume doubling time (VDT) is usually less than 400 d for malignant solid lung nodules, but VDT takes longer for subsolid nodules. Solid nodules, greater than or equal to 8 mm in diameter, nodules in the upper lobe of the lung with burr margins, and a history of smoking or tumor disease should be highly suspicious of malignancy and treated with aggressive surveillance and further workup. For pure ground-glass lung nodules of 5-10 mm in diameter, CT should be reviewed once a year for 3 years. For pure ground-glass lung nodules >10 mm in diameter, repeat CT 3 months after the initial CT examination. If the lesion persists, non-surgical biopsy or surgical treatment is recommended unless the patient cannot tolerate surgery. For partially solid pulmonary nodules less than 8 mm in diameter, CT scans should be performed at 3, 12, and 24 months after the first examination for strict periodic follow-up, followed by I CT scan per year for 3 years, and non-surgical biopsy or surgical treatment should be performed as soon as an enlargement of the solid portion is detected during follow-up. For partially solid pulmonary nodules >8 mm in diameter, CT should be repeated 3 months after the first tear, and if the lesion persists, PET scan, non-surgical biopsy, and surgical treatment should be actively managed. For subsolid pulmonary nodules >15 mm in diameter, no follow-up CT is required, and active management should be performed directly.